Brugada Syndrome
Background
Brugada syndrome may present with VT (syncope or cardiac arrest)
- Anatomically abnormal right ventricular outflow tract
- Autosomal dominant Na+ channelopathy (± structurally normal heart)
- Particularly prevalent in 30-50 yo, Asian men
- ↑ vagal tone (particularly post exercise) may precipitate arrhythmia
- Exertional (or immediately post exertional) syncope is always pathological
- ECG findings may only be seen after Flecainide, procainamide or a β-blocker
ECG Δ may be triggered by:
ECG
- ECG changes may be intermittent & transient
- Unusual or saddle ST↑ (>2mm) in V1 - V3
- Partial or complete RBBB (± T inversion)
- J point elevation
Treatment
- Check for electrolyte abN (K+, Ca++ & Mg++)
- Refer cardiology to confirm Dx (& advise on sport etc.)
- Implantable defibrillator
Content by Dr Íomhar O' Sullivan. Last review Dr ÍOS 14/04/24.
